BDBM10880 AZA::AZA2::AZM acetazolamide::Acerazolamide, AAZ::Acetazolamide::Acetazolamide (AAZ)::Acetazolamide (AZA)::Acetazolamide (AZM)::Acetazolamide, 5::Acetazolamide, AAZ::Acetazolamide, AZA::Acetazolamide, AZM::CHEMBL20::N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)acetamide::Sulfonamide, 1::US10172837, Acetazolamide::US11278534, Example acetazolamide::US11535599, Example acetazolamide::sulfonamide 1
SMILES CC(=O)Nc1nnc(s1)S(N)(=O)=O
InChI Key InChIKey=BZKPWHYZMXOIDC-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 111 hits for monomerid = 10880
Affinity DataKi: 8.60nMAssay Description:Inhibition of human CAH4 expressed in Escherichia coli BL21 (DE3) by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataKi: 11nMAssay Description:Inhibition of human secreted carbonic anhydrase 4 measured by CO2 hydration reaction assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 4(Bos taurus (bovine))
University of Agricultural Sciences and Veterinary Medicine
University of Agricultural Sciences and Veterinary Medicine
Affinity DataKi: 70nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 4(Bos taurus (bovine))
University of Agricultural Sciences and Veterinary Medicine
University of Agricultural Sciences and Veterinary Medicine
Affinity DataKi: 70nM ΔG°: -9.75kcal/molepH: 7.4 T: 2°CAssay Description:Inhibition assay using human Carbonic anhydrase I and II and bovine carbonic anhydrase IV. More data for this Ligand-Target Pair
TargetCarbonic anhydrase 4(Bos taurus (bovine))
University of Agricultural Sciences and Veterinary Medicine
University of Agricultural Sciences and Veterinary Medicine
Affinity DataKi: 70nMAssay Description:Inhibitory activity against CA4 isolated from bovine lung microsomesMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 4(Bos taurus (bovine))
University of Agricultural Sciences and Veterinary Medicine
University of Agricultural Sciences and Veterinary Medicine
Affinity DataKi: 70nMAssay Description:Inhibitory activity against carbonic anhydrase IV from bovine lung microsomesMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 4(Bos taurus (bovine))
University of Agricultural Sciences and Veterinary Medicine
University of Agricultural Sciences and Veterinary Medicine
Affinity DataKi: 70nMAssay Description:Inhibitory activity against bovine carbonic anhydrase IV (bCAIV)More data for this Ligand-Target Pair
TargetCarbonic anhydrase 4(Bos taurus (bovine))
University of Agricultural Sciences and Veterinary Medicine
University of Agricultural Sciences and Veterinary Medicine
Affinity DataKi: 70nMAssay Description:Inhibitory activity against bovine carbonic anhydrase isozyme IV isolated from bovine lung microsomes, by esterase assay method.More data for this Ligand-Target Pair
TargetCarbonic anhydrase 4(Bos taurus (bovine))
University of Agricultural Sciences and Veterinary Medicine
University of Agricultural Sciences and Veterinary Medicine
Affinity DataKi: 70nMAssay Description:Compound was evaluated for inhibition against bovine carbonic anhydrase IVMore data for this Ligand-Target Pair
Affinity DataKi: 70nMAssay Description:Inhibition of recombinant human membrane-associated carbonic anhydrase 4 assessed as inhibition of CO2 hydration preincubated for 15 mins prior to te...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 4(Bos taurus (bovine))
University of Agricultural Sciences and Veterinary Medicine
University of Agricultural Sciences and Veterinary Medicine
Affinity DataKi: 70nMAssay Description:Inhibitory activity against carbonic anhydrase isolated from bovine lung microsome (bCA IV)More data for this Ligand-Target Pair
Affinity DataKi: 74nMAssay Description:Inhibition of recombinant human CA4 preincubated for 15 mins by measured for 10 to 100 secs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 74nMAssay Description:Inhibition of recombinant human CA4 pre-incubated for 15 mins measured by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 74nMAssay Description:Inhibition of recombinant human CA4 preincubated for 15 mins by phenol red dye-based stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 74nMAssay Description:Inhibition of recombinant human carbonic anhydrase 4 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 74nMAssay Description:Inhibition of recombinant human carbonic anhydrase 4 incubated for 1 hr prior to testing measured for 10 to 100 secs by phenol red-based stopped-flow...More data for this Ligand-Target Pair
Affinity DataKi: 74nMAssay Description:Inhibition of human carbonic anhydrase 4 incubated for 15 mins prior to testing by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 74nMAssay Description:Inhibition of human recombinant carbonic anhydrase 4 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 74nMAssay Description:Inhibition of recombinant human carbonic anhydrase 4 incubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red-based stopped-f...More data for this Ligand-Target Pair
Affinity DataKi: 74nMAssay Description:Inhibition of human recombinant carbonic anhydrase 4 preincubated with enzyme for 1 hr prior to testing by phenol red-based stopped-flow CO2 hydratio...More data for this Ligand-Target Pair
Affinity DataKi: 74nMAssay Description:Inhibition of human recombinant carbonic anhydrase 4 pre-incubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 74nMAssay Description:Inhibition of carbonic anhydrase-4 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 74nM ΔG°: -9.04kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
Affinity DataKi: 74nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 74nM ΔG°: -9.72kcal/molepH: 7.4 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 74nM ΔG°: -9.66kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 74nMAssay Description:Inhibition of human recombinant CA4 after 15 mins by CO2 hydration stopped flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 74nMAssay Description:Inhibition of human carbonic anhydrase 4More data for this Ligand-Target Pair
Affinity DataKi: 74nMpH: 7.5Assay Description:Inhibition of human carbonic anhydrase 4 preincubated for 15 mins at pH 7.5 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 74nMAssay Description:Inhibition of human carbonic anhydrase 4 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 74nMAssay Description:Inhibition of human carbonic anhydrase 4 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 74nMAssay Description:Inhibition of human carbonic anhydrase 4 after 15 mins by Lineweaver-Burk plotMore data for this Ligand-Target Pair
Affinity DataKi: 74nMAssay Description:Inhibition of human CA4 by CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 74nMAssay Description:Inhibition of human recombinant carbonic anhydrase 4 preincubated for 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 74nM ΔG°: -9.72kcal/moleT: 2°CAssay Description:Inhibition of human recombinant carbonic anhydrase 4 preincubated for 15 mins at room temperature/6 hrs at 4 deg C by stopped-flow CO2 hydration assa...More data for this Ligand-Target Pair
Affinity DataKi: 74nMAssay Description:Inhibition of human recombinant CA4 expressed in Escherichia coli preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 74nMAssay Description:Inhibition of human recombinant carbonic anhydrase 4 preincubated for 15 mins prior to testing by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 74nMAssay Description:Inhibition of human recombinant carbonic anhydrase 4 expressed in Escherichia coli BL21 (DE3) by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 74nMAssay Description:Inhibition of recombinant human carbonic anhydrase 4 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 74nMAssay Description:Inhibition of recombinant human carbonic anhydrase 4 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 74nMAssay Description:Inhibition of human recombinant carbonic anhydrase-4 using CO2 as substrate preincubated for 10 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 74nMAssay Description:Inhibition of recombinant human carbonic anhydrase-4 assessed as reduction in enzyme-catalyzed hydration activity using CO2 as substrate preincubated...More data for this Ligand-Target Pair
Affinity DataKi: 74nMAssay Description:Inhibition of recombinant human CA4 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 74nMAssay Description:Inhibition of recombinant human carbonic anhydrase 4 incubated for 10 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 74nMAssay Description:Inhibition of human recombinant carbonic anhydrase 4 incubated for 15 mins prior to testing by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 74nMAssay Description:Inhibition of recombinant human membrane bound carbonic anhydrase 4 pretreated for 15 mins prior to testing measured for 10 to 100 secs by phenol red...More data for this Ligand-Target Pair
Affinity DataKi: 74nMAssay Description:Inhibition of human CA4 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 74nMAssay Description:Inhibition of human recombinant CA4 by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 74nMAssay Description:Inhibition of human recombinant full length CA4 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 74nMAssay Description:Inhibition of human CA4 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair